Enzalutamide

Docetaxel Extends Enzalutamide Effectiveness

Docetaxel Extends Enzalutamide Effectiveness

PRESIDE is the first evidence that docetaxel might reduce enzalutamide resistance when given together. It also suggests that triplet therapy may be helpful in men who have already developed castration resistance.

The FDA has Agreed to Grant A Priority Review of Xtandi for Men Who are Castrate Sensitive

According to a press release issued by Astellas and Pfizer that the FDA has granted a priority review to enzalutamide (Xtandi) for the treatment of men with metastatic hormone-sensitive prostate cancer.

ADT With and Without Xtandi in Men with Metastatic Hormone Sensitive Prostate Cancer: The ARCHES Trial

After a median follow-up of 14.4 months, the men who had Xtandi along with ADT experienced an improved radiographic progression-free survival advantage over those who had only ADT, regardless of their prior treatment. 

The ENZAMET Study: Adding Enzalutamide to ADT in Metastatic Hormone-Sensitive Prostate Cancer Extends Survival

The trial found that 80% of men with metastatic hormone-sensitiveprostate cancer who received enzalutamide (Xtandi) along with standard-of-care treatment (ADT) were alive after three years, compared with just 72% of men who received other nonsteroidal antiandrogens along with standard ADT therapy.