Advanced Prostate Cancer

Statins, Vitamin D and Zytiga

Statins, Vitamin D and Zytiga

A post hoc analysis of two randomized clinical trials shows some evidence that taking statins and vitamin D supplements might reduce the risk of death in men who have castrate resistant prostate cancer (CRPC) who are also taking the drug Zytiga (abiraterone acetate or AA) with prednisone.

First Data Release from The Metastatic Prostate Cancer Project

The project’s goal is to have thousands and thousands of men with metastatic prostate cancer share their medical records, their DNA and their tumor tissue so that we can understand the genomics of this disease, learn how it progresses and how resistance to treatments develop. 

Clinical Experience of 100 Consecutive Men Treated with Lu-177 

At the ESMO  2018 Conference that was recently concluded, there was a report of the clinical experience of 100 men with metastatic castrate resistant prostate cancer (mCRPC) who were consecutively treated with Lu-177 PSMA-I&T Radioligand Therapy. 

Statin Use Along with Zytiga or Xtandi Extends Survival in Men Who Failed Chemotherapy 

Statins have been in the prostate cancer news feeds for a long time.  They are believed to potentiate the effects of the anti-hormonal agents used to treat metastatic castration-resistant prostate cancer (mCRPC). Different stages of prostate cancer as well as different treatment exposures might change the efficacy of statins.